Principal Investigator:
Prof. Claudio Grassi, Dr. Salvatore Fusco
Ricercatori coinvolti:
Luciano Giaco’ PhD, Davide Guido PhD, Fernando Palluzzi PhD, Beatrice Tropea MSc
Obiettivo:
The aim of the research was to compare protein palmitoylation values got from mice set in three different experimental conditions: wild type, Alzheimer’s disease (AD) mutated and pharmacologically treated (against AD). 3719 different proteins were evaluated in relation to replicated measurements for each experimental condition. Bioinformatic analysis on proteomic data was implemented, and a protein-gene conversion (annotation) was performed on the relevant proteins.