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Home / Facilities / Real World Data

Real World Data

Artificial Intelligence and Big Data processing services for the integration of clinical data and the development of predictive models to support diagnosis, therapies and clinical processes.
Head: Prof. Andrea Damiani
Email: realworlddata@www.gemelligenerator.it
Description

The Real World Data (RWD) facility offers services to extract, analyze and process large data volumes through advanced Artificial Intelligence and machine learning techniques. The facility is specialized in the development of automated extraction systems (BOTS), predictive models capable to simulate complex multidimensional clinical scenarios (Avatar) and “Data Products” through aggregation and synthesis of Data Marts. Furthermore, the RWD facility creates secondary databases, which continue to update and bridge their data with other databanks, to integrate and process heterogeneous data from clinic laboratories, images, -omics and wearables.

The primary purpose of the facility is to offer support systems for information availability to the benefit the patient and community, ensuring availability of information, which is easy to interpret by professionals.

The project has received financial support of Research and Innovation (R&I) Fund, Axis II – Action II.3 delivered from Italian Ministry for University and Research and European Union.

Development of a software platform and a wide range of solution and services for digital healthcare, based on Data Science and Artificial Intelligence, aimed at research and clinical practice. READ MORE

Real World Data Project Logos
Services of Real World Data
Data Clustering

Through this service, specialized clinical data sets for each single pathology ('Data Mart') can be created collecting and integrating data of different sources to provide a consistent and patient-centered view...

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Predictive Models – BOT

Predictive Models or BOT are an automated sequence of computer algorithms providing quantitative indicators (e.g., in form of probability or percentage incidence) related to clinical outcomes of various kinds...

Read
Predictive Models – AVATAR

AVATAR are models of synthetic representation of patient types (so-called “virtual patients” or “digital twins”) created by analyzing the clinical history of similar patient groups in terms of symptoms, demographic aspects and evolution of the clinical picture...

Read
Organization of trials – E-care systems

In partnership with Innovation Sprint, the GENERATOR RWD team integrated the use of the Healthentia platform into clinical trials, which allows: remote clinical monitoring and assistance of patients involved in prospective clinical trials, use of an integrated dashboard...

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Organization of trials – Distributed Learning

Implementation of distributed learning systems to carry out multicenter studies in full compliance with the principles of privacy and protection of both data and methodologies adopted.

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Organization of trials – Sandbox

The sandbox is a virtual environment available at the Generator Center, which allows partner researchers, who carry out joint studies with the RWD Generator team, to operate in full compliance with Privacy and GDPR regulations (without directly accessing sensitive data) having at the same time a wide range of methods and algorithms for searches of common interest available.

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Organization of trials – Virtual Patients

Using data clustering services and predictive models, the Real World Data team supports the execution and optimization of studies, through introduction of phenotypic clusters⎯virtual patients⎯or development of simulated endpoints⎯virtual trials⎯which can reduce the overall execution time of the study.

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Projects
A.I. APACHE
Read
AI-BASED SELECTION OF CANDIDATES FOR BREAST CLINICAL TRIALS
Read
Bacterium
Read
Breast KPIs
Read
Breast Rt CM.BOT
Read
Classification of pneumonia by chest ultrasound images
Read
Clinical course of COVID-19 positive patients under chronic immunosuppressive therapy.
Read
Colon and Rectum
Read
CORONA.BOT and CORONABED.BOT
Read
COVID-19 monitoring and support service for Gemelli Collaborators
Read
Critic
Read
CRONO
Read
DATA MART BREAST
Read
DataMart COVID-19
Read
Early predictors of clinical outcomes of COVID-19 outbreak in an Italian single centre
Read
Emulation trial sulle terapie anti-COVID
Read
GEMINI-8
Read
INTERFACE
Read
LiCO
Read
Miraggyo
Read
Multivariate analysis of a longitudinal data mart for Spinal Muscular Atrophy
Read
Privacy Preserving Data Mining
Read
Radiology.BOT
Read
SIBILLA
Read
Tracer RT
Read
Team
Prof. Andrea Damiani
Head A.I. strategy, R&D
Dr. Luca Boldrini
Scientific coordinator of the Radiomics partner facility
Ing. Carlotta Masciocchi
Projects coordinator, PhD
Dr. Luca Tagliaferri (MD, PhD)
Clinical Research coordinator
Dr. Nikola Dino Capocchiano
Data Scientist
Dr.ssa Maria Vittoria De Girolamo
Research nurse
Ing. Agni Delvinioti
Data Scientist
Dr.ssa Nicoletta Di Giorgi
Data Scientist
Ing. Benedetta Gottardelli
PhD candidate
Dr.ssa Chiara Iacomini
Data Manager
Dr. Jacopo Lenkowicz
Data Scientist
Dr.ssa Livia Lilli
Data Scientist
Dr.ssa Alice Luraschi
Program manager
Ing. Giulio Pagliari
Project Manager
Dr. Riccardo Rinaldi
Data Manager
Ing. Mariachiara Savino
PhD candidate
Dr.ssa Federica Tomassini
Research nurse
Project Collaborators
Prof. Vincenzo Valentini
Prof. Giovanni Scambia
Prof. Rocco Domenico Alfonso Bellantone
Prof. Sergio Alfieri
Prof. Massimo Antonelli
Prof. Roberto Benarbei
Prof. Paolo Calabresi
Prof. Cesare Colosimo
Prof. Guido Costamagna
Prof. Filippo Crea
Prof. Ruggero De Maria Marchiano
Prof. Valerio De Stefano
Prof. Domenico D'Ugo
Prof. Maria Antonietta Gambacorta
Prof. Antonio Gasbarrini
Prof. Felice Giuliante
Prof. Raffaele Landolfi
Prof. Massimo Massetti
Prof. Eugenio Maria Mercuri
Prof. Alessandro Olivi
Prof. Gaetano Paludetti
Prof. Ketty Peris
Prof. Maurizio Sanguinetti
Prof. Gianpaolo Tortora
Prof. Andrea Urbani
Dr. Luca Boldrini
Dr. Luca Tagliaferri
Dr. Anna Rita Alitto
Dr. Rosa Autorino
Dr. Francesco Cellini
Dr. Silvia Chiesa
Dr. Giuditta Chiloiro
Dr. Giuseppe Ferdinando Colloca
Dr. Giulia De Angelis
Prof.ssa Maria Gabriella Ferrandina
Dr. Gabriella Macchia
Dr. Fabio Marazzi
Dr. Valeria Masiello
Dr. Mariangela Massaccesi
Dr. Riccardo Maviglia
Dr. Elisa Meldolesi
Dr. Francesco Miccichè
Dr. Rita Murri
Dr. Andrea Bellieni
Dr. Ivo Boskoski
Dr. Pietro Caliandro
Dr. Andrea Chiricozzi
Dr. Antonella Cingolani
Dr. Giorgia Coratti
Prof. Carmela De Crea
Dr. Giacomo Della Marca
Dr. Giuseppe Maria Della Pepa
Dr. Giovanni Di Cintio
Dr. Massimo Fantoni
Dr. Claudio Fiorillo
Dr. Laura Lorenzon
Dr. Amato Infante
Dr. Simona Lucibello
Dr. Pier Paolo Mattogno
Dr. Caterina Mele
Dr. Luca Miele
Dr. Mauro Monforte
Dr. Armando Orlandi
Prof. Roberto Pola
Dr. Francesca Ponziani
Dr. Angelo Porfidia
Dr. Giuseppe Quero
Prof. Marco Raffaelli
Dr. Emanuele Rocco Villani

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